Explain the term target molecules or drug targets as used in medicinal chemistry.
In medicinal chemistry, drug targets refer to the key molecules involved in certain metabolic pathways that result in specific diseases. Carbohydrates, proteins, lipids, and nucleic acids are examples of drug targets.
Drugs are chemical agents designed to inhibit these target molecules by binding with the active sites of the key molecules.
Why do soaps not work in hard water?
Explain the following terms with suitable examples
(i) cationic detergents
(ii) anionic detergents and
(iii) non-ionic detergents.
What are food preservatives ?
Sleeping pills are recommended by doctors to the patients suffering from sleeplessness but it is not advisable to take its doses without consultation with the doctor, Why?
How do antiseptics differ from disinfectants ? Give one example of each.
Why is use of aspartame limited to cold foods and drinks?
What are the main constituents of dettol?
With reference to which classification has the statement, ranitidine is an antacid been given?
Write the chemical equation for preparing sodium soap from glyceryl oleate and glyceryl palmitate. Structural formulae of these compounds are given below.
(i) (C15H31COO)3 C3H5 - Glyceryl palmitate
(ii)(C17H33COO)3 C3H5 - Glyceryl oleate
Name a substance which can be used as an antiseptic as well as disinfectant.
For the reaction R → P, the concentration of a reactant changes from 0.03 M to 0.02 M in 25 minutes. Calculate the average rate of reaction using units of time both in minutes and seconds.
Write the formulas for the following coordination compounds:
(i) Tetraamminediaquacobalt (III) chloride
(ii) Potassium tetracyanonickelate(II)
(iii) Tris(ethane-1,2-diamine) chromium(III) chloride
(iv) Amminebromidochloridonitrito-N-platinate(II)
(v) Dichloridobis(ethane-1,2-diamine)platinum(IV) nitrate
(vi) Iron(III) hexacyanoferrate(II)
(i) Write structures of different isomeric amines corresponding to the molecular formula, C4H11N
(ii) Write IUPAC names of all the isomers.
(iii) What type of isomerism is exhibited by different pairs of amines?
Why are solids rigid?
Write any two characteristics of Chemisorption.
Write the structures of the following compounds.
(i) α-Methoxypropionaldehyde
(ii) 3-Hydroxybutanal
(iii) 2-Hydroxycyclopentane carbaldehyde
(iv) 4-Oxopentanal
(v) Di-sec-butyl ketone
(vi) 4-Fluoroacetophenone
Which of the ores mentioned in Table 6.1 can be concentrated by magnetic separation method?
Why are pentahalides more covalent than trihalides?
Silver atom has completely filled d orbitals (4d10) in its ground state. How can you say that it is a transition element?
Glucose or sucrose are soluble in water but cyclohexane or benzene (simple six membered ring compounds) are insoluble in water. Explain.
What is glycogen? How is it different from starch?
How would you determine the standard electrode potential of the system Mg2+ | Mg?
Write the electronic configurations of the elements with the atomic numbers 61, 91, 101, and 109.
Compare the stability of +2 oxidation state for the elements of the first transition series.
What happens when white phosphorus is heated with concentrated NaO Hsolution in an inert atmosphere of CO2?
Name the common elements present in the anode mud in electrolytic refining of copper. Why are they so present ?
What type of substances would make better permanent magnets, ferromagnetic or ferrimagnetic. Justify your answer.
Explain why is ortho nitrophenol more acidic than ortho methoxyphenol?
Predict the products of the following reactions:
(i)
(ii)
(iii)
(iv)
What is the effect of temperature on the rate constant of a reaction? How can this temperature effect on rate constant be represented quantitatively?
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