Explain the term target molecules or drug targets as used in medicinal chemistry.
In medicinal chemistry, drug targets refer to the key molecules involved in certain metabolic pathways that result in specific diseases. Carbohydrates, proteins, lipids, and nucleic acids are examples of drug targets.
Drugs are chemical agents designed to inhibit these target molecules by binding with the active sites of the key molecules.
Why do soaps not work in hard water?
Explain the following terms with suitable examples
(i) cationic detergents
(ii) anionic detergents and
(iii) non-ionic detergents.
What are food preservatives ?
Sleeping pills are recommended by doctors to the patients suffering from sleeplessness but it is not advisable to take its doses without consultation with the doctor, Why?
How do antiseptics differ from disinfectants ? Give one example of each.
Why is use of aspartame limited to cold foods and drinks?
With reference to which classification has the statement, ranitidine is an antacid been given?
What are the main constituents of dettol?
Write the chemical equation for preparing sodium soap from glyceryl oleate and glyceryl palmitate. Structural formulae of these compounds are given below.
(i) (C15H31COO)3 C3H5 - Glyceryl palmitate
(ii)(C17H33COO)3 C3H5 - Glyceryl oleate
What are artificial sweetening agents? Give two examples.
For the reaction R → P, the concentration of a reactant changes from 0.03 M to 0.02 M in 25 minutes. Calculate the average rate of reaction using units of time both in minutes and seconds.
Write the formulas for the following coordination compounds:
(i) Tetraamminediaquacobalt (III) chloride
(ii) Potassium tetracyanonickelate(II)
(iii) Tris(ethane-1,2-diamine) chromium(III) chloride
(iv) Amminebromidochloridonitrito-N-platinate(II)
(v) Dichloridobis(ethane-1,2-diamine)platinum(IV) nitrate
(vi) Iron(III) hexacyanoferrate(II)
(i) Write structures of different isomeric amines corresponding to the molecular formula, C4H11N
(ii) Write IUPAC names of all the isomers.
(iii) What type of isomerism is exhibited by different pairs of amines?
Why are solids rigid?
Write any two characteristics of Chemisorption.
Write the structures of the following compounds.
(i) α-Methoxypropionaldehyde
(ii) 3-Hydroxybutanal
(iii) 2-Hydroxycyclopentane carbaldehyde
(iv) 4-Oxopentanal
(v) Di-sec-butyl ketone
(vi) 4-Fluoroacetophenone
Which of the ores mentioned in Table 6.1 can be concentrated by magnetic separation method?
Why are pentahalides more covalent than trihalides?
Silver atom has completely filled d orbitals (4d10) in its ground state. How can you say that it is a transition element?
Glucose or sucrose are soluble in water but cyclohexane or benzene (simple six membered ring compounds) are insoluble in water. Explain.
What are enzymes? Write in brief the mechanism of enzyme catalysis.
A solution of glucose in water is labelled as 10% w/w, what would be the molality and mole fraction of each component in the solution? If the density of solution is 1.2 g mL-1, then what shall be the molarity of the solution?
Mention the conditions required to maximise the yield of ammonia.
(i) What is meant by the term 'coordination number'?
(ii) What is the coordination number of atoms:
(a) in a cubic close-packed structure?
(b) in a body-centred cubic structure?
Action of soap is due to emulsification and micelle formation. Comment.
Why does O3 act as a powerful oxidising agent?
Complete each synthesis by giving missing starting material, reagent or products
(i)
(ii)
(iii)
(iv)
(v)
(vi)
Two elements A and B form compounds having formula AB2 and AB4. When dissolved in 20 g of benzene (C6H6), 1 g of AB2 lowers the freezing point by 2.3 Kwhereas 1.0 g of AB4 lowers it by 1.3 K. The molar depression constant for benzene is 5.1 Kkg mol-1. Calculate atomic masses of A and B.
What happens when D-glucose is treated with the following reagents? (i)HI (ii)Bromine water (iii)HNO3
Calculate the mass of ascorbic acid (Vitamin C, C6H8O6) to be dissolved in 75 g of acetic acid to lower its melting point by 1.5°C. Kf= 3.9 K kg mol-1.
not bad