Discuss the main steps in the digestion of proteins as the food passes through different parts of the alimentary canal.
The digestion of proteins begins in the stomach and is completed in the small intestine. The enzymes that act on proteins are known as proteases.
Digestion in the stomach:
The digestive juice secreted in the gastric glands present on the stomach walls is called gastric juice. The main components of gastric juice are HCl, pepsinogen, and rennin. The food that enters the stomach becomes acidic on mixing with this gastric juice.
The acidic medium converts inactive pepsinogen into active pepsin. The active pepsin then converts proteins into proteases and peptides.
Proteins Proteoses + Peptides
The enzyme rennin plays an important role in the coagulation of milk.
Digestion in the small intestine:
The food from the stomach is acted upon by three juices present in the small intestine – pancreatic juice and intestinal juice (known as succus entericus).
Action of pancreatic juice
Pancreatic juice contains a variety of inactive enzymes such as trypsinogen, chymotrypsinogen, and carboxypeptidases. The enzymes are present in an inactivated state. The enzyme enterokinase secreted by the intestinal mucosa activates trypsinogen into trypsin.
TrypsinogenTrypsin + Inactive peptide
The activated trypsin then activates the other enzymes of pancreatic juice.
Chymotrypsinogen is a proteolytic enzyme that breaks down proteins into peptides.
Chymotrypsinogen Chymotrypsin
Proteins Peptides
Carboxypeptidases act on the carboxyl end of the peptide chain and help in releasing the last amino acids.
PeptidesSmaller peptide chain + Amino acids
Action of bile juice
Bile juice has bile salts such as bilirubin and biliverdin which break down large, fat globules into smaller globules so that pancreatic enzymes can easily act on them. This process is known as emulsification of fats. Bile juice also makes the medium alkaline and activates lipase. Lipase then breaks down fats into diglycerides and monoglycerides.
Action of intestinal juice
Intestinal juice contains a variety of enzymes. Pancreatic amylase digests polysaccharides into disaccharides. Disaccharidases such as maltase, lactase, sucrase, etc., further digest the disaccharides.
The proteases hydrolyse peptides into dipeptides and finally into amino acids.
Amino acids
Pancreatic lipase breaks down fats into diglycerides and monoglycerides.
The nucleases break down nucleic acids into nucleotides and nucleosides.
Bile juice contains no digestive enzymes, yet it is important for digestion. Why?
How does butter in your food gets digested and absorbed in the body?
State the role of pancreatic juice in digestion of proteins.
Describe the process of digestion of protein in stomach.
Choose the correct answer among the following:
(a) Gastric juice contains
(i) pepsin, lipase and rennin
(ii) trypsin lipase and rennin
(iii) trypsin, pepsin and lipase
(iv) trypsin, pepsin and renin
(b) Succus entericus is the name given to
(i) a junction between ileum and large intestine
(ii) intestinal juice
(iii) swelling in the gut
(iv) appendix
How are polysaccharides and disaccharides digested?
Describe the digestive role of chymotrypsin. What two other digestive enzymes of the same category are secreted by its source gland?
Answer briefly:
(a) Why are villi present in the intestine and not in the stomach?
(b) How does pepsinogen change into its active form?
(c) What are the basic layers of the wall of alimentary canal?
(d) How does bile help in the digestion of fats?
Which of the following is not correct?
(a) Robert Brown discovered the cell.
(b) Schleiden and Schwann formulated the cell theory.
(c) Virchow explained that cells are formed from pre-existing cells.
(d) A unicellular organism carries out its life activities within a single cell.
Describe the role of liver, lungs and skin in excretion.
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Clear and open answers
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a small mistake. bile does not play any role in protein digestion