Define oxygen dissociation curve. Can you suggest any reason for its sigmoidal pattern?
The oxygen dissociation curve is a graph showing the percentage saturation of oxyhaemoglobin at various partial pressures of oxygen.
The curve shows the equilibrium of oxyhaemoglobin and haemoglobin at various partial pressures.
In the lungs, the partial pressure of oxygen is high. Hence, haemoglobin binds to oxygen and forms oxyhaemoglobin.
Tissues have a low oxygen concentration. Therefore, at the tissues, oxyhaemoglobin releases oxygen to form haemoglobin.
The sigmoid shape of the dissociation curve is because of the co-operative binding of oxygen to haemoglobin. As the first oxygen molecule binds to haemoglobin, it increases the affinity for the second molecule of oxygen to bind. Subsequently, haemoglobin attracts more oxygen.Hence Haemoglobin is a positively co-operative protein.
Distinguish between
(a) IRV and ERV
(b) Inspiratory capacity and Expiratory capacity
(c) Vital capacity and Total lung capacity
What is the effect of pCO2 on oxygen transport?
Which of the following is not correct?
(a) Robert Brown discovered the cell.
(b) Schleiden and Schwann formulated the cell theory.
(c) Virchow explained that cells are formed from pre-existing cells.
(d) A unicellular organism carries out its life activities within a single cell.
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