Recombinant proteins are obtained from the recombinant DNA technology. This technology involves the transfer of specific genes from an organism into another organism using vectors and restriction enzymes as molecular tools.
Ten recombinant proteins used in medical practice are −
Recombinant protein |
Therapeutic use |
|
1. |
Insulin |
Treatment for type I diabetes mellitus |
2. |
Interferon-α |
Used for chronic hepatitis C |
3. |
Interferon -β |
Used for herpes and viral enteritis |
4. |
Coagulation factor VII |
Treatment of haemophilia A |
5. |
Coagulation factor IX |
Treatment of haemophilia B |
6. |
DNAase I |
Treatment of cystic fibrosis |
7. |
Anti-thrombin III |
Prevention of blood clot |
8. |
Interferon B. |
For treatment of multiple sclerosis |
9. |
Human recombinant growth hormone |
For promoting growth in an individual |
10. |
Tissue plasminogen activator |
Treatment of acute myocardial infection |
Fill in the blanks:
(a) Humans reproduce __________. (asexually/sexually)
(b) Humans are__________. (oviparous/viviparous/ovoviviparous)
(c) Fertilization is __________ in humans. (external/internal)
(d) Male and female gametes are __________. (diploid/haploid)
(e) Zygote is __________. (diploid/haploid)
(f) The process of release of the ovum from a mature follicle is called__________.
(g) Ovulation is induced by a hormone called the __________.
(h) The fusion of male and female gametes is called _____________.
(i) Fertilisation takes place in _____________.
(j) Zygote divides to form _____________which is implanted in uterus.
(k) The structure which provides vascular connection between fetus and uterus is called ____________.
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