Academic session 2026-27, Chapter 10 in the current curriculum.
Welcome to the NCERT Solutions for Class 12 Biology - Chapter Biotechnology and its Application. This page offers a step-by-step solution to the specific question from Exercise 1, Question 5: What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.. With detailed answers and explanations for each chapter, students can strengthen their understanding and prepare confidently for exams. Ideal for CBSE and other board students, this resource will simplify your study experience.
Gene therapy is a technique for correcting a defective gene through gene manipulation. It involves the delivery of a normal gene into the individual to replace the defective gene, for example, the introduction of gene for adenosine deaminase (ADA) in ADA deficient individual. The adenosine deaminase enzyme is important for the normal functioning of the immune system. The individual suffering from this disorder can be cured by transplantation of bone marrow cells. The first step involves the extraction of lymphocyte from the patient’s bone marrow. Then, a functional gene for ADA is introduced into lymphocytes with the help of retrovirus. These treated lymphocytes containing ADA gene are then introduced into the patient’s bone marrow. Thus, the gene gets activated producing functional T- lymphocytes and activating the patient’s immune system.
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Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 1 , Question 5: What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.....
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Nice answer
Nice answer J Rajen saikia
Very nic answer thanx
Gene therapy in a broader sense include correction of non genetic disorders like cardiovascular disorder, as well by delivering a normal gene.