What is gene therapy? Illustrate using t | Class 12 Biology Chapter Biotechnology and its Application, Biotechnology and its Application NCERT Solutions

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Academic session 2026-27, Chapter 10 in the current curriculum.

Welcome to the NCERT Solutions for Class 12 Biology - Chapter Biotechnology and its Application. This page offers a step-by-step solution to the specific question from Exercise 1, Question 5: What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.. With detailed answers and explanations for each chapter, students can strengthen their understanding and prepare confidently for exams. Ideal for CBSE and other board students, this resource will simplify your study experience.

Question 5: What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
Answer:

Gene therapy is a technique for correcting a defective gene through gene manipulation. It involves the delivery of a normal gene into the individual to replace the defective gene, for example, the introduction of gene for adenosine deaminase (ADA) in ADA deficient individual. The adenosine deaminase enzyme is important for the normal functioning of the immune system. The individual suffering from this disorder can be cured by transplantation of bone marrow cells. The first step involves the extraction of lymphocyte from the patient’s bone marrow. Then, a functional gene for ADA is introduced into lymphocytes with the help of retrovirus. These treated lymphocytes containing ADA gene are then introduced into the patient’s bone marrow. Thus, the gene gets activated producing functional T- lymphocytes and activating the patient’s immune system.

Study Tips for Answering NCERT Questions:

NCERT questions are designed to test your understanding of the concepts and theories discussed in the chapter. Here are some tips to help you answer NCERT questions effectively:

  • Read the question carefully and focus on the core concept being asked.
  • Reference examples and data from the chapter when answering questions about Biotechnology and its Application.
  • Review previous year question papers to get an idea of how such questions may be framed in exams.
  • Practice answering questions within the time limit to improve your speed and accuracy.
  • Discuss your answers with your teachers or peers to get feedback and improve your understanding.

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Comments

  • Rajen saikia
  • Feb 26, 2019

Nice answer

  • Rajen saikia
  • Feb 26, 2019

Nice answer J Rajen saikia

  • Rohit sharma
  • Jul 27, 2017

Very nic answer thanx

  • Vinod Bharadwaj
  • Apr 05, 2015

Gene therapy in a broader sense include correction of non genetic disorders like cardiovascular disorder, as well by delivering a normal gene.

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Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 1 , Question 5: What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.....

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